Integrative Systems Biology, Metabolomics and Cancer    Department of Biochemistry and Molecular Biology

NEW!!

                       Would you like to do a phD in our group? More info HERE.

For a post-doc stay in our group, please contact Dra. Marta Cascante Serratosa  
 

Cancer therapy

	Study of the differences of glucose regulation metabolism among normal and different tumoral cell lines
	Design of antitumoral therapy strategies based on the inhibition of different steps of pentoses-phosphate pathway
	Characterization of antitumoral drug effects at cellular and metabolic level

Drug development from natural products for pharmacological, cosmetic or food industries

Study of the antitumoral and antioxidant properties of bioactive polyphenols extracted out of subproducts from the agricultural and forest industries

Control and regulation analysis of biochemical systems with biomedical or biothecnological purposes

	Modeling of metabolic pathways and prediction of genetic manipulation consequences towards a therapeutic or industrial purpose
	Sofware package development using Mathematica(R) for the analysis and modeling of metabolic pathways
	Design analysis and optimization of metabolic pathway regulatory patterns
	Theoretical development and experimental application of  Metabolic Control Analysis (MCA) and  Biochemical Systems Theory (BST)
	Modeling of biochemical systems using kinetic or stocastic methods
	Study of enzyme-enzyme interactions and biopolimers-enzymes binding

Metabolomics & fluxomics

	Metabolite measurement by GC/MS and LC/MS in samples with a special biomedical, biotechnological or industrial interest
	Software development and application for metabolic fluxes quantification by using kinetic information and experimental metabolomic data
	Characterization of metabolic adaptations that accompany: cell differentiation cell death tumorogenesis oncogene transformation drug treatments