Biologia de Sistemes Integrativa, Metabolòmica i Càncer 

Departament de Bioquímica i Biomedicina Molecular

 English    Catala

INICI - MEMBRES DEL GRUP - PUBLICACIONS - PROJECTES ACTUALS - ENLLAÇOS

 

PUBLICACIONS (ÚLTIMS CINC ANYS)

Selivanov, V.A.; Benito, A.; Miranda, A.; Aguilar, E.; Polat, I.H.; Centelles, J.J.; Jayaraman, A.; Lee, P.W.; Marin, S.; Cascante, M. (2017). MIDcor, an R-program for deciphering mass interferences in mass spectra of metabolites enriched in stable isotopes. BMC Bioinformatics 18(1), 88.

Marín de Mas, I.; Fanchon, E.; Papp, B.; Kalko, S.; Roca, J.; Cascante, M. (2017). Molecular mechanisms underlying COPD-muscle dysfunction unveiled through a systems medicine approach. Bioinformatics. 33(1), 95-103.

Tarrado-Castellarnau, M.; de Atauri, P.; Cascante, M. (2016). Oncogenic regulation of tumor metabolic reprogramming. Oncotarget. 7(38), 62726-62753.

Escolà, A.; Crespo, M.; López, C.; Quirante, J.; Jayaraman, A.; Polat, I.H.; Badía, J.; Baldomà, L.; Cascante, M. (2016). On the stability and biological behavior of cyclometallated Pt(IV) complexes with halido and aryl ligands in the axial positions. Bioorg Med Chem. 24(22), 5804-5815.

Beger, R.D.; Dunn, W.; Schmidt, M.A.; Gross, S.S.; Kirwan, J.A.; Cascante, M.; Brennan, L.; Wishart, D.S.; Oresic, M.; Hankemeier, T.; Broadhurst, D.I.; Lane, A.N.; Suhre, K.; Kastenmüller, G.; Sumner, S.J.; Thiele, I.; Fiehn, O.; Kaddurah-Daouk, R.; for “Precision Medicine and Pharmacometabolomics Task Group”-Metabolomics Society Initiative. (2016). Metabolomics enables precision medicine: "A White Paper, Community Perspective". Metabolomics. 12(10), 149.

Diaz-Moralli, S.; Aguilar, E.; Marin, S.; Coy, J.F.; Dewerchin, M.; Antoniewicz, M.R.; Meca-Cortés, O.; Notebaert, L.; Ghesquière, B.; Eelen, G.; Thomson, T.M.; Carmeliet, P.; Cascante, M. (2016). A key role for transketolase-like 1 in tumor metabolic reprogramming. Oncotarget 7(32), 51875-51897.

Aguilar, E.; Marin de Mas, I.; Zodda, E.; Marín, S.; Morrish, F.; Selivanov, V.; Meca-Cortés, Ó.; Delowar, H.; Pons, M.; Izquierdo, I.; Celià-Terrassa, A.; de Atauri, P.; Centelles, J.J.; Hockenbery, D.; Thomson, T.M.; Cascante, M. (2016). Metabolic reprogramming and dependencies associated with epithelial cancer stem cells uncoupled from epithelial-mesenchymal transition. Stem Cells 34(5),1163-1176.

Alekseev, A.E.; Guzun, R.; Reyes, S.; Pison, C.; Schlattner, U.; Selivanov, V.A.; Cascante, M. (2016). Restrictions in ATP diffusion within sarcomeres can provoke ATP-depleted zones impairing exercise capacity in chronic obstructive pulmonary disease. Biochimica et Biophysica Acta – General Subjects 1860(10), 2269-2278.

Foguet, C.; Marin, S.; Selivanov, V.A.; Fanchon, E.; Lee, W.N.; Guinovart, J.J.; de Atauri, P.; Cascante, M. (2016). HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data. PLoS Computational Biology 12(4), e1004899.

Gonçalves, B.M.; Salvador, J.A.; Marín, S.; Cascante, M. (2016). Synthesis and anticancer activity of novel fluorinated asiatic acid derivatives. European Journal of Medicinal Chemistry 114, 101-117.

Gonçalves, B.M.F.; Salvador, J.A.R.; Santos, D.S.M.; Marin, S.; Cascante, M. (2016). Design, synthesis, and biological evaluation of novel asiatic acid derivatives as potential anticancer agents. RSC Advances 6(45), 39296-39309.

Gonçalves, B.M.F.; Salvador, J.A.R.; Marín, S.; Cascante, M. (2016). Synthesis and biological evaluation of novel asiatic acid derivatives with anticancer activity. RSC Advances 6(5), 3967-3985.

Reyes-Zurita, F.J.; Rufino-Palomares, E.E.; García-Salguero, L.; Peragón, J.; Medina, P.P.; Parra, A.; Cascante, M.; Lupiáñez, J.A. (2016). Maslinic acid, a natural triterpene, induces a death receptor-mediated apoptotic mechanism in Caco-2 p53-deficient colon adenocarcinoma cells. PLoS One 11(1), e0146178 (2016).

Tényi, Á.; de Atauri, P.; Gomez-Cabrero, D.; Cano, I.; Clarke, K.; Falciani, F.; Cascante, M.; Roca, J.; Maier, D. (2016). ChainRank, a chain prioritisation method for contextualisation of biological networks. BMC Bioinformatics 17(1), 17.

Salek, R.M.; Neumann, S.; Schober, D.; Hummel, J.; Billiau, K.; Kopka, J.; Correa, E.; Reijmers, T.; Rosato, A.; Tenori, L.; Turano, P.; Marin, S.; Deborde, C.; Jacob, D.; Rolin, D.; Dartigues, B.; Conesa, P.; Haug, K.; Rocca-Serra, P.; O'Hagan, S.; Hao, J.; van Vliet, M.; Sysi-Aho, M.; Ludwig, C.; Bouwman, J.; Cascante, M.; Ebbels, T.; Griffin, J.L.; Moing, A.; Nikolski, M.; Oresic, M.; Sansone, S.A.; Viant, M.R.; Goodacre, R.; Günther, U.L.; Hankemeier, T.; Luchinat, C.; Walther, D.; Steinbeck, C. (2015). COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access. Metabolomics 11(6), 1587-1597.

Tarrado-Castellarnau, M.; Cortés, R.; Zanuy, M.; Tarragó-Celada, J.; Polat, I.H.; Hill, R.; Fan, T.W.; Link, W.; Cascante, M. (2015). Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition. Pharmacological research 102, 218-234.

Balcells, C.; Pastor, I.; Pitulice, L.; Hernández, C.; Via, M.; Garcés, J.L.; Madurga, S.; Vilaseca, E.; Isvoran, A.; Cascante, M.; Mas, F. (2015). Macromolecular crowding upon in-vivo-like enzyme-kinetics: effect of enzyme-obstacle size ratio. New Frontiers in Chemistry 24(1), 3-16.

Albert, J.; Bosque, R.; Crespo, M.; Granell, J.; López, C.; Martín, R.; González, A.; Jayaraman, A.; Quirante, J.; Calvis, C.; Badía, J.; Baldomà, L.; Font-Bardia, M.; Cascante, M.; Messeguer, R. (2015). Neutral and ionic platinum compounds containing a cyclometallated chiral primary amine: synthesis, antitumor activity, DNA interaction and topoisomerase I-cathepsin B inhibition. Dalton transactions 44(30), 13602-13614.

Binns, M.; de Atauri, P.; Vlysidis, A.; Cascante, M.; Theodoropoulos, C. (2015). Sampling with poling-based flux balance analysis: optimal versus sub-optimal flux space analysis of Actinobacillus succinogenes. BMC Bioinformatics 16, 49.

Romero, M., M. Zanuy, E. Rosell, M. Cascante, J. Piulats, M. Font-Bardia, J. Balzarini, E. De Clerq & M. D. Pujol (2015). Optimization of xanthatin extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties. European Journal of Medicinal Chemistry, 90, 491-6.

Albert, J., R. Bosque, M. Crespo, G. Garcia, J. Granell, C. Lopez, M. V. Lovelle, R. Qadir, A. Gonzalez, A. Jayaraman, E. Mila, R. Cortes, J. Quirante, C. Calvis, R. Messeguer, J. Badia, L. Baldoma & M. Cascante (2014). Cyclopalladated primary amines: A preliminary study of antiproliferative activity through apoptosis induction. European Journal of Medicinal Chemistry, 84, 530-536.

Alcarraz-Vizan, G., S. Sanchez-Tena, M. P. Moyer & M. Cascante (2014). Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: Trichostatin A as a case study. Biochimica Et Biophysica Acta-General Subjects, 1840, 1634-1639.

Balcells, C., I. Pastor, E. Vilaseca, S. Madurga, M. Cascante & F. Mas (2014). Macromolecular Crowding Effect upon in Vitro Enzyme Kinetics: Mixed Activation-Diffusion Control of the Oxidation of NADH by Pyruvate Catalyzed by Lactate Dehydrogenase. Journal of Physical Chemistry B, 118, 4062-4068.

Cano, I., M. Lluch-Ariet, D. Gomez-Cabrero, D. Maier, S. Kalko, M. Cascante, J. Tegner, F. Miralles, D. Herrera, J. Roca & C. C. Synergy (2014). Biomedical research in a Digital Health Framework. Journal of Translational Medicine, 12.

Cano, I., V. Selivanov, D. Gomez-Cabrero, J. Tegner, J. Roca, P. D. Wagner & M. Cascante (2014). Oxygen Pathway Modeling Estimates High Reactive Oxygen Species Production above the Highest Permanent Human Habitation. PLoS ONE, 9.

Cano, I., A. Tenyi, C. Schueller, M. Wolff, M. M. Huertas Miguelanez, D. Gomez-Cabrero, P. Antczak, J. Roca, M. Cascante, F. Falciani & D. Maier (2014). The COPD Knowledge Base: enabling data analysis and computational simulation in translational COPD research. Journal of Translational Medicine, 12.

Cascante, M., P. de Atauri, D. Gomez-Cabrero, P. Wagner, J. J. Centelles, S. Marin, I. Cano, F. Velickovski, I. Marin de Mas, D. Maier, J. Roca & P. Sabatier (2014). Workforce preparation: the Biohealth computing model for Master and PhD students. Journal of Translational Medicine, 12.

Cortes, R., M. Tarrado-Castellarnau, D. Talancon, C. Lopez, W. Link, D. Ruiz, J. Joan Centelles, J. Quirante & M. Cascante (2014). A novel cyclometallated Pt(II)-ferrocene complex induces nuclear FOXO3a localization and apoptosis and synergizes with cisplatin to inhibit lung cancer cell proliferation. Metallomics, 6, 622-633.

de Mas, I. M., E. Aguilar, A. Jayaraman, I. H. Polat, A. Martin-Bernabe, R. Bharat, C. Foguet, E. Mila, B. Papp, J. J. Centelles & M. Cascante (2014). Cancer cell metabolism as new targets for novel designed therapies. Future Medicinal Chemistry, 6, 1791-1810.

Escola, A., M. Crespo, J. Quirante, R. Cortes, A. Jayaraman, J. Badia, L. Baldoma, T. Calvet, M. Font-Bardia & M. Cascante (2014). Exploring the Scope of Pt-2(4-FC6H4)(4)(mu-SEt2)(2) as a Precursor for New Organometallic Platinum(II) and Platinum(IV) Antitumor Agents. Organometallics, 33, 1740-1750.

Gomez-Cabrero, D., M. Lluch-Ariet, J. Tegner, M. Cascante, F. Miralles, J. Roca & C. C. Synergy (2014a) Synergy-COPD: a systems approach for understanding and managing chronic diseases. Journal of Translational Medicine, 12.

Gomez-Cabrero, D., J. Menche, I. Cano, I. Abugessaisa, M. Huertas-Miguelanez, A. Tenyi, I. Marin de Mas, N. A. Kiani, F. Marabita, F. Falciani, K. Burrowes, D. Maier, P. Wagner, V. Selivanov, M. Cascante, J. Roca, A.-L. Barabasi & J. Tegner (2014). Systems Medicine: from molecular features and models to the clinic in COPD. Journal of Translational Medicine, 12.

Guzman, S., S. Marin, A. Miranda, V. A. Selivanov, J. J. Centelles, R. Harmancey, F. Smih, A. Turkieh, Y. Durocher, A. Zorzano, P. Rouet & M. Cascante (2014). C-13 metabolic flux analysis shows that resistin impairs the metabolic response to insulin in L6E9 myotubes. BMC systems biology, 8.

Jose Ramirez-Bajo, M., P. de Atauri, F. Ortega, H. V. Westerhoff, J. Lluis Gelpi, J. J. Centelles & M. Cascante (2014). Effects of Cadmium and Mercury on the Upper Part of Skeletal Muscle Glycolysis in Mice. PLoS ONE, 9.

Marin de Mas, I., E. Aguilar, A. Jayaraman, I. H. Polat, A. Martin-Bernabe, R. Bharat, C. Foguet, E. Mila, B. Papp, J. J. Centelles & M. Cascante (2014). Cancer cell metabolism as new targets for novel designed therapies. Future Medicinal Chemistry, 6, 1791-810.

Martin-Bernabe, A., R. Cortes, S. G. Lehmann, M. Seve, M. Cascante & S. Bourgoin-Voillard (2014). Quantitative Proteomic Approach to Understand Metabolic Adaptation in Non-Small Cell Lung Cancer. Journal of Proteome Research, 13, 4695-4704.

Miralles, F., D. Gomez-Cabrero, M. Lluch-Ariet, J. Tegner, M. Cascante, J. Roca & C. C. Synergy (2014). Predictive medicine: outcomes, challenges and opportunities in the Synergy-COPD project. Journal of Translational Medicine, 12.

Molinar-Toribio, E., J. Perez-Jimenez, S. Ramos-Romero, L. Lluis, V. Sanchez-Martos, N. Taltavull, M. Romeu, M. Pazos, L. Mendez, A. Miranda, M. Cascante, I. Medina & J. Lluis Torres (2014). Cardiovascular Disease-Related Parameters and Oxidative Stress in SHROB Rats, a Model for Metabolic Syndrome. PLoS ONE, 9.

Obiol-Pardo, C., G. Alcarraz-Vizan, S. Diaz-Moralli, M. Cascante & J. Rubio-Martinez (2014). Design of an interface peptide as new inhibitor of human glucose-6-phosphate dehydrogenase. Journal of Molecular Graphics & Modelling, 49, 110-117.

Pastor, I., L. Pitulice, C. Balcells, E. Vilaseca, S. Madurga, A. Isvoran, M. Cascante & F. Mas (2014). Effect of crowding by Dextrans in enzymatic reactions. Biophysical Chemistry, 185, 8-13.

Roca, J., C. Vargas, I. Cano, V. Selivanov, E. Barreiro, D. Maier, F. Falciani, P. Wagner, M. Cascante, J. Garcia-Aymerich, S. Kalko, I. Marin De Mas, J. Tegner, J. Escarrabill, A. Agusti, D. Gomez-Cabrero & C. C. Synergy (2014). Chronic Obstructive Pulmonary Disease heterogeneity: challenges for health risk assessment, stratification and management. Journal of Translational Medicine, 12.

Schoors, S., K. De Bock, A. R. Cantelmo, M. Georgiadou, B. Ghesquiere, S. Cauwenberghs, A. Kuchnio, B. W. Wong, A. Quaegebeur, J. Goveia, F. Bifari, X. Wang, R. Blanco, B. Tembuyser, I. Cornelissen, A. Bouche, S. Vinckier, S. Diaz-Moralli, H. Gerhardt, S. Telang, M. Cascante, J. Chesney, M. Dewerchin & P. Carmeliet (2014). Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis. Cell Metabolism, 19, 37-48.

Albert, J., R. Bosque, M. Crespo, J. Granell, C. Lopez, R. Cortes, A. Gonzalez, J. Quirante, C. Calvis, R. Messeguer, L. Baldoma, J. Badia & M. Cascante (2013). Pt(II) complexes with (N,N ') or (C,N,E)(-) (E = N,S) ligands: Cytotoxic studies, effect on DNA tertiary structure and structure-activity relationships. Bioorganic & Medicinal Chemistry, 21, 4210-4217.

Carreras, A., J. Antonio Mesa, M. Cascante, J. Lluis Torres & L. Julia (2013). High electron transfer capacity of thio-derivatives of tea catechins measured using a water soluble stable free radical and their effects on colon cancer cells. New Journal of Chemistry, 37, 2043-2050.

Cascante, M., S. Sanchez-Tena, D. Lizarraga, M. A. Reed, J. B. Carrigan, S. Diaz-Moralli, G. Alcarraz-Vizan, F. J. Reyes-Zurita, J. J. Centelles, M. P. Vinardell, J. A. Lupianez, V. Noe, C. J. Ciudad, J. L. Torres & U. Guenther (2013). Combined study of microarray expression and NMR metabolic profile as a powerful approach to identify potential chemopreventive activity of natural products. Febs Journal, 280, 628-629.

Diaz-Moralli, S., M. Tarrado-Castellarnau, A. Miranda & M. Cascante (2013). Targeting cell cycle regulation in cancer therapy. Pharmacology & Therapeutics, 138, 255-271.

Kaplon, J., L. Zheng, K. Meissl, B. Chaneton, V. A. Selivanov, G. Mackay, S. H. van der Burg, E. M. E. Verdegaal, M. Cascante, T. Shlomi, E. Gottlieb & D. S. Peeper (2013). A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence. Nature, 498, 109-+.

Rajeeve, V., W. Pearce, M. Cascante, B. Vanhaesebroeck & P. R. Cutillas (2013). Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth. Biochemical Journal, 450, 619-628.

Reyes-Zurita, F. J., E. E. Rufino-Palomares, P. P. Medina, E. Leticia Garcia-Salguero, J. Peragon, M. Cascante & J. A. Lupianez (2013). Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells. Biochimie, 95, 2157-2167.

Ruiz-Ontanon, P., J. L. Orgaz, B. Aldaz, A. Elosegui-Artola, J. Martino, M. T. Berciano, J. A. Montero, L. Grande, L. Nogueira, S. Diaz-Moralli, A. Esparis-Ogando, A. Vazquez-Barquero, M. Lafarga, A. Pandiella, M. Cascante, V. Segura, J. A. Martinez-Climent, V. Sanz-Moreno & J. L. Fernandez-Luna (2013). Cellular Plasticity Confers Migratory and Invasive Advantages to a Population of Glioblastoma-Initiating Cells that Infiltrate Peritumoral Tissue. STEM CELLS, 31, 1075-1085.

Sanchez-Tena, S., G. Alcarraz-Vizan, S. Marin, J. Lluis Torres & M. Cascante (2013). Epicatechin Gallate Impairs Colon Cancer Cell Metabolic Productivity. Journal of Agricultural and Food Chemistry, 61, 4310-4317.

Sanchez-Tena, S., D. Lizarraga, A. Miranda, M. P. Vinardell, F. Garcia-Garcia, J. Dopazo, J. L. Torres, F. Saura-Calixto, G. Capella & M. Cascante (2013). Grape antioxidant dietary fiber inhibits intestinal polyposis in Apc(Min/) mice: relation to cell cycle and immune response. Carcinogenesis, 34, 1881-1888.

Sanchez-Tena, S., F. J. Reyes-Zurita, S. Diaz-Moralli, M. Pilar Vinardell, M. Reed, F. Garcia-Garcia, J. Dopazo, J. A. Lupianez, U. Guenther & M. Cascante (2013). Maslinic Acid-Enriched Diet Decreases Intestinal Tumorigenesis in Apc(Min/+) Mice through Transcriptomic and Metabolomic Reprogramming. PLoS ONE, 8.

Sanchez-Tena, S., P. Vizan, P. K. Dudeja, J. J. Centelles & M. Cascante (2013). Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. Biochimica Et Biophysica Acta-Molecular Basis of Disease, 1832, 2264-2270.

Talancon, D., C. Lopez, M. Font-Bardia, T. Calvet, J. Quirante, C. Calvis, R. Messeguer, R. Cortes, M. Cascante, L. Baldoma & J. Badia (2013). Diastereomerically pure platinum(II) complexes as antitumoral agents. The influence of the mode of binding {(N), (N,O)(-) or (C,N)}(-) of (1S,2R) - (eta(5)-C5H5) Fe{(eta(5)-C5H4) - CH=N - CH(Me) - CH(OH) - C6H5) and the arrangement of the auxiliary ligands. Journal of Inorganic Biochemistry, 118, 1-12.

Angeles-Martinez, L., M. Binns, C. Theodoropoulos, P. de Atauri & M. Cascante. (2012). Thermodynamically constrained Flux and Control Analysis of Escherichia coli. In 22 European Symposium on Computer Aided Process Engineering, eds. I. D. L. Bogle & M. Fairweather, 1377-1381.

Bosca, L., P. Traves, M. Pimentel-Santillana, P. de Atauri, S. Marin & M. Cascante (2012). Metabolomic analysis of macrophage activation and relevance of the cross-talk between energetic metabolism and polarized gene expression. Journal of Immunology, 188.

Carreras, A., M. Luisa Mateos-Martin, A. Velazquez-Palenzuela, E. Brillas, M. Cascante, L. Julia & J. Lluis Torres (2012). Punicalagin and Catechins Contain Polyphenolic Substructures That Influence Cell Viability and Can Be Monitored by Radical Chemosensors Sensitive to Electron Transfer. Journal of Agricultural and Food Chemistry, 60, 1659-1665.

Carreras, A., M. Luisa Mateos-Martin, A. Velazquez-Palenzuela, E. Brillas, S. Sanchez-Tena, M. Cascante, L. Julia & J. Lluis Torres (2012). Punicalagin and Catechins Contain Polyphenolic Substructures That Influence Cell Viability and Can Be Monitored by Radical Chemosensors Sensitive to Electron Transfer. Journal of Agricultural and Food Chemistry, 60, 4763-4763.

Cascante, M., P. Martin-Sanz, P. Traves, M. Pimentel-Santillana, P. Prieto, M. Fernandez & L. Bosca (2012). Macrophage polarization and metabolic fate. Febs Journal, 279, 24-24.

Cortes, R., M. Crespo, L. Davin, R. Martin, J. Quirante, D. Ruiz, R. Messeguer, C. Calvis, L. Baldoma, J. Badia, M. Font-Bardia, T. Calvet & M. Cascante (2012). Seven-membered cycloplatinated complexes as a new family of anticancer agents. X-ray characterization and preliminary biological studies. European Journal of Medicinal Chemistry, 54, 557-566.

Diaz-Moralli, S., A. Ramos-Montoya, S. Marin, A. Fernandez-Alvarez, M. Casado & M. Cascante (2012). Target metabolomics revealed complementary roles of hexose- and pentose-phosphates in the regulation of carbohydrate-dependent gene expression. American Journal of Physiology-Endocrinology and Metabolism, 303, E234-E242.

Lizarraga, D., M. P. Vinardell, V. Noe, J. H. van Delft, G. Alcarraz-Vizan, S. G. van Breda, Y. Staal, U. L. Guenther, J. B. Carrigan, M. A. Reed, C. J. Ciudad, J. L. Torres & M. Cascante (2012). A lyophilized Red Grape Pomace Containing Proanthocyanidin-Rich Dietary Fiber Induces Genetic and Metabolic Alterations in Colon Mucosa of Female C57BL/6J mice. Journal of Nutrition, 142, 396-396.

Obiol-Pardo, C., G. Alcarraz-Vizan, M. Cascante & J. Rubio-Martinez (2012). Diphenyl Urea Derivatives as Inhibitors of Transketolase: A Structure-Based Virtual Screening. PLoS ONE, 7.

Pey, J., A. Rubio, C. Theodoropoulos, M. Cascante & F. J. Planes (2012). Integrating tracer-based metabolomics data and metabolic fluxes in a linear fashion via Elementary Carbon Modes. Metabolic Engineering, 14, 344-353.

Rodriguez, D. A., G. Alcarraz-Vizan, S. Diaz-Moralli, M. Reed, F. P. Gomez, F. Falciani, U. Guenther, J. Roca & M. Cascante (2012). Plasma metabolic profile in COPD patients: effects of exercise and endurance training. Metabolomics, 8, 508-516.

Rodriguez, D. A., S. Kalko, E. Puig-Vilanova, M. Perez-Olabarria, F. Falciani, J. Gea, M. Cascante, E. Barreiro & J. Roca (2012). Muscle and blood redox status after exercise training in severe COPD patients. Free Radical Biology and Medicine, 52, 88-94.

Sanchez-Tena, S., M. L. Fernandez-Cachon, A. Carreras, M. Luisa Mateos-Martin, N. Costoya, M. P. Moyer, M. J. Nunez, J. L. Torres & M. Cascante (2012). Hamamelitannin from Witch Hazel (Hamamelis virginiana) Displays Specific Cytotoxic Activity against Colon Cancer Cells. Journal of Natural Products, 75, 26-33.

Selivanov, V. A., M. Cascante, M. Friedman, M. F. Schumaker, M. Trucco & T. V. Votyakova (2012). Multistationary and Oscillatory Modes of Free Radicals Generation by the Mitochondrial Respiratory Chain Revealed by a Bifurcation Analysis. PLoS computational biology, 8.

Sineiro, J., M. Rubilar, M. Cascante, E. Alvarez, M. Sanchez & M. J. Nunez. (2012). Potential Therapeutic Applications of Common Agro-Food Byproducts and Chilean Wild Plants. In Emerging Trends in Dietary Components for Preventing and Combating Disease, eds. B. S. Patil, G. K. Jayaprakasha, K. N. C. Murthy & N. P. Seeram, 117-130.

Traves, P. G., P. de Atauri, S. Marin, M. Pimentel-Santillana, J.-C. Rodriguez-Prados, I. Marin de Mas, V. A. Selivanov, P. Martin-Sanz, L. Bosca & M. Cascante (2012). Relevance of the MEK/ERK Signaling Pathway in the Metabolism of Activated Macrophages: A Metabolomic Approach. Journal of Immunology, 188, 1402-1410.

Zanuy, M., A. Ramos-Montoya, O. Villacanas, N. Canela, A. Miranda, E. Aguilar, N. Agell, O. Bachs, J. Rubio-Martinez, M. Dolors Pujol, W.-N. P. Lee, S. Marin & M. Cascante (2012). Cyclin-dependent kinases 4 and 6 control tumor progression and direct glucose oxidation in the pentose cycle. Metabolomics, 8, 454-464.

               

INICI - MEMBRES DEL GRUP - PUBLICACIONS - PROJECTES ACTUALS - ENLLAÇOS